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Phytochemistry
Volume 61, Issue 4, October 2002, Pages 461-464

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DOI: 10.1016/S0031-9422(02)00140-1
PII: S0031-9422(02)00140-1
Copyright © 2002 Elsevier Science Ltd. All rights reserved.

Iridoid and phenolic diglycosides from Canthium berberidifolium

Tripetch Kanchanapoom^a, Ryoji Kasai^b and Kazuo Yamasaki ^,^,^b

^a Department of Pharmaceutical Botany and Pharmacognosy, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand
^b Institute of Pharmaceutical Sciences, Faculty of Medicine, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan

Received 7 January 2002; revised 10 April 2002. Available online 1 May 2002.

Abstract

An iridoid diglycoside, 6-O- small beta, Greek --apiofuranosyl-mussaenosidic acid, and four phenolic diglycosides, canthosides A_¯D, were isolated from the aerial part of Canthium berberidifolium, along with seven known compounds. Structural elucidations were based on analyses of spectroscopic data.

Graphical Abstract

From the aerial parts of Canthium berberidifolium, 6'-O- small beta, Greek --apiofuranosyl-mussaenosidic acid and canthosides A_¯D were isolated, together with seven known compounds.
View Image

Author Keywords: Canthium berberidifolium; Rubiaceae; Iridoid diglycoside; Phenolic diglycosides; Canthosides A_¯D; Hydroquinone diglycoside

Article Outline

1. Introduction
2. Results and discussion
3. Experimental 3.1. General 3.2. Plant material 3.3. Extraction and isolation 3.4. 6-O---Apiofuranosyl-mussaenosidic acid (2) 3.5. Canthoside A (7) 3.6. Canthoside B (9) 3.7. Canthoside C (10) 3.8. Canthoside D (11)
Acknowledgements
References

Table 1. NMR spectral data of compound 2 (400 MHz for ¹H NMR and 100 MHz for ¹³C NMR, CD₃OD)

(13K)

Table 2. ¹H NMR spectral data of compounds 7, 9_¯11 (400 MHz, CD3OD)a

(31K)

Table 3. ¹³C NMR spectral data of compounds 7, 9_¯11 (400 MHz, CD₃OD)

(10K)

References

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Corresponding author. Tel.: 82-257-5285; fax: 82-257-5289; email: kazuoy@hiroshima-u.ac.jp

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Phytochemistry
Volume 61, Issue 4, October 2002, Pages 461-464

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